CPSA Shanghai 2015

Connecting the Dots:
Sharing Science Across Disciplines Helps Projects Progress

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Poster Session

# Class Author Title
101 GEN Jianming Cao Development of a High Sensitivity Quantitative SPE-LC/MS/MS Assay for Bradykinin in Human Plasma Using IonKey /MS Technology
102 GEN Erin Chambers Practical Considerations for LC/MS Bioanalysis of Proteins via the Surrogate Peptide Approach
103 GEN Fuxin Chen Determination of Natamycin Content in Cake Using Ultra Performance Liquid Chromatography-Mass/Mass Spectrometry
104 GEN Tao Chen Quantitative Analysis of OATP1B1 in Human Hepatocytes of Chinese Population Using Liquid Chromatography Tandem Mass Spectrometry
105 YSE Jia Chen Development of a Physiologically-based pharmacokinetic model to predict systemic and cerebrospinal icotinib exposure in cancer patients 
106 YSE Kan Chen Is incidence of skin rash driven by peak concentration or wild type EGFR IC50 cover by pharmacokinetics for EGFR-TKIs?
107 YSE Jia Chen Population pharmacokinetic/pharmacodynamic/survival modeling analysis of icotinib in Chinese non-small cell lung cancer subjects
108 GEN Wenqi Cui Quantitative determination of Nucleoside Triphosphate in Rat liver using liquid chromatography–tandem mass spectrometry
109 YSE Xinge Cui Quantitative determination of Nucleoside Triphosphate in Rat liver using liquid chromatography–tandem mass spectrometry
110 YSE Ziru Dai Characterization of a highly selective ratiometric two-photon fluorescent probe for human cytochrome P450 1A and its biological applications
111 YSE Jiajia Dong Comparative disposition of intravenous catechols, derived from Salvia miltiorrhiza roots (Danshen), in rats and mechanisms governing their systemic exposure
112 YSE Chaoying Hu Single and Multiple Dose Pharmacokinetics, pharmacodynamics and safety of darapladib (a novel Lp-PLA2 enzyme inhibitor) in healthy Chinese subjects
113 GEN Liang Huang Investigation on ISR failure and the subsequent solutions to overcome the assay variability
114 GEN Bo Li What Quality of a Commercial Kit (Immunoassay) Needed ——Key parameters in a method for quantitative determination of target protein
115 YSE Jerry Li Adaptation of An in Vitro Model for Assessing the Reactivity of Acyl Glucuronides in Drug Discovery
116 YSE Yang Liu A mechanism-based model to describe oral glucose tolerance test data in Chinese type 2 diabetics
117 YSE Xinwei Liu Colonic Metabolites of Flavonols in Rats and Dogs after Oral Administration of GBE50, A Standardized Ginkgo biloba Leaf Extract
118 YSE Cai Liu Human Cytochrome P450 Enzymes and Hepatic Microsomal Thiol Methyltransferase Involved in Stereoselective Formation and Methylation of Pharmacologically Active Metabolite of Clopidogrel
119 GEN Russell Mortishire-Smith High Sensitivity Bioanalysis for Small Drug-Like Compounds in Human Plasma using Microflow LC and High Resolution Mass Spectrometry
120 GEN Long Na Evaluation of drug-induced hepatotoxicity with five biomarkers in sandwich cultured rat hepatocytes  
121 GEN Lirui Qiao Applying LC/MS Natural Product Application Solution with UNIFI for the Identification of the Chemical and Herbal Components from an Unknown Traditional Chinese Medicine Product  
122 GEN Suzi Qin Extraction of Telmisartan from Human Plasma Utilizing Cleanert SLE Plate with High Capacity
123 INN Gary Valaskovic Ease-of-use and sensitivity with nanospray: An integrated chip-based solution incorporating column temperature control, long columns, and nebulization.
124 GEN Yi Tao Development and Validation of an HPLC-MS/MS Method for Determination of Suramin in Monkey Plasma
125 YSE Xun Tao Intestinal Lymphatic Absorption into Consideration When Constructing Physiologically Based Pharmacokinetic Model (PBPK)
126 GEN Gary Valaskovic PicoFuze: Integration enables high-flow nanospray/microspray with conventional LC-ESI-MS
127 GEN Dan Wang Aristolochic acid I associated target identified by a monoclonal antibody against aristolochic acid I and II using immunoprecipitation and LC-MS/MS
128 GEN Wan Wang Comparison of Various Sample Pretreatment Methods for Monitoring Arachidonic Acid in Plasma
129 YSE Jing-Jing Wu Characterization of gomisin A as a novel isoform-specific probe for selective detection of human cytochrome P450 3A4
130 YSE Zhixiong Xiang Evaluation of the relative bioavailability of dabigatran etexilate mesylate in beagle dogs
131 GEN Ling Xu An LC/MS/MS Based Strategy for Quantification of Monoclonal Antibodies and Antibody-conjugated Drugs for Developing Antibody Drug Conjugates
132 YSE Yumei Yan Impact of incubation time on determination of unbound fractions in blood and brain homogenate
133 GEN Xingxin Yang Development of an Efficient Screening Method for Screening Potential Bioactive Compounds Binding to Mitochondria from Herbal Medicines by Combining Centrifugal Ultrafiltration with Liquid Chromatography/Mass Spectrometry
134 INN Hui Wang Development and Validation of LC-MS/MS Method for the Quantitation of Infliximab in Human Serum
135 YSE Nating Zhang Systemic exposure to and disposition of phthalides from Ligusticum chuanxiong rhizomes and Angelica sinensis roots after intravenous administration of XueBiJing injection in human subjects and rats
136 YSE Jinqiang Zhang Utilization of MDCK permeability and short oral absorption model for GI restricted drug discovery
137 YSE Xin Zheng A simplification of population pharmacokinetic/pharmacodynemic model based time-dependent kinetics of Red Blood Cell (RBC) binding model and its application to drug CPRC-1 in human
138 YSE Chenchun Zhong Chemical Profiling of Ginkgo Biloba Leaves and Extracts
139 GEN Lei Zhou Oxidative and Reductive Activation of Nimesulide: Possibly Irrelevant with Hepatotoxicity
140 GEN Yunting Zhu In Vitro and In Vivo Metabolism of TPN729 and Assessment of Its Drug-Drug Interaction Potential
141 YSE Dan Wu A simple, rapid and reliable liquid chromatography-mass spectrometry method for determination of methotrexate in human plasma and its application to therapeutic drug monitoring
142 GEN Tony Chen In silico Modeling Can Predict the Unforeseen Renal Failure Caused by SGX523, a c-MET Kinase Inhibitor
143 GEN Ying Zhou Population pharmacokinetics and Monte Carlo dosing simulation of HR7056 anesthesia in Chinese healthy subjects
144 GEN Chen Chen Organic Anion-Transporting Polypeptides Contribute to the Hepatic Uptake of Berberine