CPSA Shanghai 2018

New Horizons in Drug Discovery and Development:
Bioanalysis, Biomarkers and ADME

Preliminary Meeting Program     Wednesday | Thursday | Friday

Updated 13 December 2017

Wednesday 星期三 18 April

10:00 am

Renaissance Shanghai
4th Floor Lobby

Registration Open

1:00 PM - 3:30 PM

Ballroom I

Workshop

Introduction to Drug Discovery

Workshop Leader: Cornelis Hop, Genentech

Cornelis Hop, Genentech

Zhengyin Yan, Genentech

Jeff Zhang, Novartis

1:00 PM - 3:30 PM

Ballroom II

Workshop

Supporting Clinical Trials in China
(presentations in Chinese)

Workshop Leaders: Dafang Zhong, Shanghai Institute of Materia Medica; Hongliang Jiang, Huazhong University of Science and Technology

4:00 PM - 4:45 PM

Ballroom II

Keynote Lecture

2018 Keynote Speaker Zaiqi Wang

Zaiqi Wang
Roche

5:00 PM - 6:00 PM

Ballroom I

Executive Roundtable

Outsourcing: Benchmarking Survey of Outsourcing Practices in the Pharmaceutical Industry

Discussion Leader: Cornelis Hop, Genentech

Benchmarking Survey of Outsourcing Practices in the Pharmaceutical Industry
Mira Hinman, Abbvie

Ajai Chaudhary, Merck

Naidong Weng, Janssen Research & Development

Helen Yu, Novartis

6:00 PM

Ballroom II

Opening Reception & Happy Hour

Greet old friends, meet new friends, and get an overview of the week’s events and activities.
Welcome to CPSA Shanghai 2018!

Sponsor's Toast

Thursday 星期四 19 April

10:00 am

Renaissance Shanghai
4th Floor Lobby

Registration Open

8:30 am - 9:00 am

Ballroom I/II

Welcome & Opening Remarks

Mike Lee

Welcome
Mike S. Lee
Milestone Development Services

Corneli Hop

Format, Objectives, Opening Remarks
Cornelis Hop
Genentech

9:00 am - 9:45 am

Ballroom I/II

Plenary Lecture

2018 Plenary Speaker Philip Timmerman

Philip Timmerman
EBF / Janssen Research & Development (ret)

9:00 am - 5:00 pm

Yangtze Ballroom

Poster Hall Open

Posters will be available all day today and Friday

10:15 am - 11:45 am

Ballroom I/II

Symposium Session

MIST and Drug Metabolism

Chairs: Simone Schadt, Abbvie; Swapan Choudary, Takeda Pharmaceuticals

MIST Case Studies
Hua Lv, Roche Shanghai

To be announced
Chandra Prakash, Agios

MIST Cases at Abbvie
Jens Sydor, Abbvie

11:00 am - 2:00 pm

4th Floor Lobby

CPSA Shanghai Expo

Where Technology and Solutions Meet!

11:30 am - 2:00 pm

Yangtze Ballroom

Poster Session

Young Scientist Award Review

12:00 pm - 1:00 pm

Lunch & Learn Workshops

Rhine

WORKSHOP

Danube

WORKSHOP

1:30 pm - 3:00 pm

PARALLEL SESSIONS : Tracks 1 - 4

Ballroom I

TRACK 1
In Vitro ADME Challenges and Advances

Chairs: Mandy Xu, Pharmaron; Zhengyin Yan, Genentech

High PPB
Zhengyin Yan, Genentech

Low Clearance Presentation
Volker Lauschke, Karolinska Institutet

Preclinical Evaluation of BBB Penetration of EGFR TKIs using in vitro and in vivo Tools
Kan Chan, AstraZeneca Asia

To be annunced
Albert Li, In Vitro ADMET Laboratories

Ballroom II

TRACK 2
Small Molecule Bioanlaysis

Chairs: Luke Bi, Covance; Jonathan Wang, Genentech

The Determination of Antiretroviral Triphosphate Metabolite in Human Peripheral Blood Mononuclear Cells
Deqing Xiao, Gilead

Bioanalytical Challenges in the Development of Combination Therapies
Jonathan Wang, Genenetech

To be announced
Minji Wei, Institute of Clinical Pharmacology, Peking University

Rhine

TRACK 3
Biomarker and Metabolomics Challenges

Chairs: Yu Tan, Abbvie; Kelly Dong, GlaxoSmithKline

To be announced
Liang Li, University of Alberta

To be announced
James Munday, Covance

To be announced
Weijun Qian, Pacific Northwest National Laboratory

Danube

TRACK 4
Pharmaceutical Development:
From Discovery to First-in-Human

Chairs: Qun Lu, Celgene; achin Lohan, Janssen Research & Development

3:30 pm - 5:00 pm

PARALLEL SESSIONS : Tracks 5 - 8

Ballroom I

TRACK 5
Impact of New Regulatory Guidances on Drug Discovery and Development, Including DDI

Chairs: Lilly Xu, ChemPartner; Hua Lv, Roche

New FDA DDI Guidance
Stephen Fowler, Roche

DDI Strategy
Lilly Xu, Chempartner

EMA FIH Guidance Impact
Cornelis Hop, Genentech

Ballroom II

TRACK 6
Issues in Regulated Bioanalysis

Chairs: Naidong Weng, Janssen Research & Development; Tianyi Zhang, Frontage

To be announced
Weiping Shao, Regeneron

To be announced
Song Zhao, Frontage

To be announced
Min Meng, ex-Covance

Rhine

TRACK 7
MALDI Imaging

Chair: Cornelis Hop, Genentech

Potential Usefulness of MS Imaging Technology with High Spatial Resolution in Pharmaceuticals
Miho Ayabe, Chugai

To be announced
Zongwei Cai, Hong Kong Baptist University

To be announced
Cristine Quaison, Genentech

Danube

TRACK 8
Hot Topics

Chairs: Jeff Zhang, Novartis; Kelly Dong, GlaxoSmithKline

Aldehyde Oxidase and its Involvement in the Metabolism of a cMet Inhibitor JAA401
Jeff Zhang, Novartis

An investigation into the prediction of in vivo clearance for a range of flavin-containing monooxygenase substrates
Danxi Li, Pharmaron

6:00 pm

Yangtze Ballroom

CPSA Social

Cocktails & Karaoke at CPSA

Whether you like to command the stage or cheer from the audience, it’s hard to have a forgettable time of karaoke.

Join colleagues and friends – old and new – to relax and unwind!

Request a song - click here!

Friday 星期五 20 April

10:00 am

Renaissance Shanghai
4th Floor Lobby

Registration Open

8:30 am - 9:15 am

Ballroom I/II

Plenary Lecture

2018 Plenary Speaker Lei Zhangg

Lei Zhang
Food & Drug Administration

9:00 am - 5:00 pm

Yangtze Ballroom

Poster Hall Open

Posters will be available all day today

9:30 am - 11:00 am

Ballroom I/II

Symposium Session

Transporters

Chairs: Jasminder Sahi, Sanofi; Ikumi Tamai, Kanazawa University

To be announced
Ikumi Tamai, Kanazawa University

To be announced
Houfu Liu, GlaxoSmithKline

To be announced
Jasminder Sahi, Sanofi

Interactions between saponins and hepatic transporters
Chuan Li, Shanghai Institute of Materia Medica

11:00 am - 2:00 pm

4th Floor Lobby

CPSA Shanghai Expo

Where Technology and Solutions Meet!

12:00 pm - 1:00 pm

Lunch & Learn Workshops

Rhine

WORKSHOP

Danube

WORKSHOP

1:30 pm - 3:00 pm

PARALLEL SESSIONS : Tracks 1 - 3

Ballroom I

TRACK 1
PBPK Modeling

Chairs: Tom Wilde, Janssen Research & Development; Avi Ghosh, Janssen Research & Development

To be announced
Tom Wilde, Janssen Research & Development

The important role of virtual Chinese population for PK/PD prediction: Perspective view from an academic institution
Pei Hu, Peking Union Medical College Hospital

Ballroom II

TRACK 2
Large Molecule Bioanlaysis

Chairs: Wenying Jian, Janssen Research & Development; Xiao-Yan Cai, WuXi AppTec

Total and Free Quantification of Therpeutic Antibodies by Liquid Chromatography-Tandem Mass Spectrometry
Ichio Onami, Chugai

Strength and Challenges of LBA on PK, ADA, NAb and Biomarker Bioanalsis for Biologic Therapeutics
Xiao-Yan Cai, WuXi AppTec

Strategies for Drug Transporter Quantitation by LC-MS
Alan Deng, Genentech

Rhine

TRACK 3
Radiolabeled Tools for Drug Development

Chairs: Stephen Dueker, BioCore; Alicia Du, Calibra Diagnostics

Human PK of 14C-Tagged Biologics
Wouter Vaes, TNO

A Benchtop CRDS Laser System for 14C Quantitation
Stephen Dueker, BioCore

The Japanese Human ADME Marker using Low Dose Studies with AMS - Regulator and Case Studies
Kohei Nozama, Sekisui

Current Status and Requirement of Radio-ADME Studies in China
Zhe-ming Gu, Value Pharmaceutical Services

3:30 pm - 5:00 pm

PARALLEL SESSIONS : Tracks 4 - 6

Ballroom I

TRACK 4
PK/PD Modeling

Chairs: Tom Wilde, Janssen Research & Development; Avi Ghosh, Janssen Research & Development

To be announced
Kas Subramanian, Syngene

To be announced
Ben Zheng, Janssen Research & Development

Ballroom II

TRACK 5
ADCs

Chairs: Keyang Xu, Genentech; Young Shin. Chungnam National University

To be announced
Jeiwook Chae,LegoChemBio

To be announced
Yue Liu, 3S Bio

To be announced
Mark Qian, Takeda Pharmaceuticals

Rhine

TRACK 6
Poster Presentation Lightening Round

Chairs: Martin Steel, McKinley Scientific; Carla Marshall-Waggett, New Objective

5:00 pm - 7:30 pm

Ballroom I/II

Dinner, Awards & Celebration

Closing Toast

Program Chair Recognition
Mike Lee, Milestone Development Services

CPSA Shanghai 2019 – Program Chair Announcement
Cornelis Hop, Genentech

Innovator Award Presentation
Kelly Dong, GlaxoSmithKline and Shaolian Zhou, Roche

Young Scientist Excellence Award Presentation
Chairs: Min Liu, Merck and Jeff Zhang, Novartis